abstract：BACKGROUND:Conventional tests are not always helpful in making a diagnosis of tuberculous pleurisy. Many studies have investigated the usefulness of interferon (IFN)-gamma measurements in pleural fluid for the early diagnosis of tuberculous pleurisy. We conducted a metaanalysis to determine the accuracy of IFN-gamma me...

journal_title：Chest

authors： Jiang J,Shi HZ,Liang QL,Qin SM,Qin XJ

更新日期：2007-04-01 00:00:00

abstract：:Human genetic variation has enormous implications for individual susceptibility to lung disease, as well as for differences in prognosis and response to therapeutic interventions. Single-nucleotide polymorphisms (SNPs) are the most common type of DNA sequence variation. An SNP is the substitution of a single base in t...

journal_title：Chest

authors： Tebbutt SJ,James A,Paré PD

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:There is controversy about whether therapy with inhaled corticosteroids (ICSs) modifies the natural history of COPD, characterized by an accelerated decline in FEV(1). METHODS:The Inhaled Steroids Effect Evaluation in COPD (ISEEC) study is a pooled study of patient-level data from seven long-term randomized...

journal_title：Chest

authors： Soriano JB,Sin DD,Zhang X,Camp PG,Anderson JA,Anthonisen NR,Buist AS,Burge PS,Calverley PM,Connett JE,Petersson S,Postma DS,Szafranski W,Vestbo J

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To assess the accuracy of dynamic expiratory CT for detecting airway malacia using bronchoscopy as the diagnostic "gold standard." MATERIALS AND METHODS:A computerized hospital information system was used to retrospectively identify all patients with bronchoscopically proven airway malacia referred for CT ai...

journal_title：Chest

authors： Lee KS,Sun MRM,Ernst A,Feller-Kopman D,Majid A,Boiselle PM

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:The impact of new-onset postoperative atrial fibrillation (NAF) on in-hospital mortality (IHM) following cardiac surgery is unknown. METHODS:All patients without preoperative atrial fibrillation undergoing isolated coronary artery bypass graft surgery (CABG) and concomitant CABG and valve surgery were ident...

journal_title：Chest

authors： Kalavrouziotis D,Buth KJ,Ali IS

更新日期：2007-03-01 00:00:00

abstract：:Pulmonary hypertension is a common finding in patients with idiopathic pulmonary fibrosis (IPF), and is associated with increased morbidity and mortality. Therapy with sildenafil has been shown to decrease pulmonary vascular resistance in patients with pulmonary fibrosis and may improve functional status. Patients wit...

journal_title：Chest

authors： Collard HR,Anstrom KJ,Schwarz MI,Zisman DA

更新日期：2007-03-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the long-term clinical course of patients with idiopathic pulmonary fibrosis (IPF) complicated with pulmonary arterial hypertension. DESIGN:Prospective analysis of consecutive IPF patients undergoing initial workup with right-heart catheterization (RHC) and pulmonary function testing (PFT)...

journal_title：Chest

authors： Hamada K,Nagai S,Tanaka S,Handa T,Shigematsu M,Nagao T,Mishima M,Kitaichi M,Izumi T

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:N-terminal pro-brain natriuretic peptide (NT-proBNP) is a byproduct of the brain natriuretic peptide (BNP) that was shown to be of prognostic value in pulmonary hypertension (PH). The role of NT-proBNP in PH has to be determined, especially under the influence of renal impairment that might lead to an accumu...

journal_title：Chest

authors： Leuchte HH,El Nounou M,Tuerpe JC,Hartmann B,Baumgartner RA,Vogeser M,Muehling O,Behr J

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Bronchoscopic microsampling (BMS) is a method in which a device consisting of a wire with a polyester probe at the tip is used to collect bronchial epithelial lining fluid with bronchoscopy. In this study, we bacteriologically investigated sample collection using BMS to incorporate BMS into diagnosis of resp...

journal_title：Chest

authors： Sasabayashi M,Yamazaki Y,Tsushima K,Hatayama O,Okabe T

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:We investigated factors related to the diagnostic sensitivity of CT-guided transbronchial biopsy (TBB) using an ultrathin bronchoscope and virtual bronchoscopy (VB) navigation for small peripheral pulmonary lesions. METHOD:We have performed this procedure on 83 patients with 85 small peripheral pulmonary le...

journal_title：Chest

authors： Shinagawa N,Yamazaki K,Onodera Y,Asahina H,Kikuchi E,Asano F,Miyasaka K,Nishimura M

更新日期：2007-02-01 00:00:00

abstract：STUDY OBJECTIVES:This multicenter study was undertaken to characterize the population of ventilator-dependent patients admitted to long-term care hospitals (LTCHs) with weaning programs, and to report treatments, complications, weaning outcome, discharge disposition, and survival in these patients. DESIGN:Observationa...

journal_title：Chest

authors： Scheinhorn DJ,Hassenpflug MS,Votto JJ,Chao DC,Epstein SK,Doig GS,Knight EB,Petrak RA,Ventilation Outcomes Study Group.

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular comorbidities have a negative impact on the health status and prognosis of patients with COPD. We determined whether nocturnal noninvasive (positive) mechanical ventilation (NIMV) can improve heart rate variability (HRV), decrease circulating natriuretic peptide levels, and improve functional ...

journal_title：Chest

authors： Sin DD,Wong E,Mayers I,Lien DC,Feeny D,Cheung H,Gan WQ,Man SF

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The immediate and long-term clinical events associated with the placement and removal of a retrievable filter (ALN filter; ALN Implants Chirurgicaux; Ghisonaccia, France) remain largely unknown. METHODS:This was a prospective cohort study with an 18-month follow-up. All consecutive patients scheduled for pl...

journal_title：Chest

authors： Mismetti P,Rivron-Guillot K,Quenet S,Décousus H,Laporte S,Epinat M,Barral FG

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:To assess the factors associated with reintubation in patients who had successfully passed a spontaneous breathing trial. METHODS:We used logistic regression and recursive partitioning analyses of prospectively collected clinical data from adults admitted to ICUs of 37 hospitals in eight countries, who had ...

journal_title：Chest

authors： Frutos-Vivar F,Ferguson ND,Esteban A,Epstein SK,Arabi Y,Apezteguía C,González M,Hill NS,Nava S,D'Empaire G,Anzueto A

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:A fixed combination of long-acting beta(2)-agonists (LABA) plus inhaled corticosteroids (ICS) has never been proven to reduce asthma exacerbations vs ICS alone in children. This 12-month, double-blind, randomized study in 341 children (age range, 4 to 11 years) with asthma uncontrolled on ICS investigated wh...

journal_title：Chest

authors： Bisgaard H,Le Roux P,Bjåmer D,Dymek A,Vermeulen JH,Hultquist C

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:In patients with advanced non-small cell lung cancer (NSCLC) treated with chemotherapy, we compared survival in patients with treated central airway obstruction to those who did not have central airway obstruction. METHODS:One hundred forty-four patients with advanced and inoperable NSCLC were included. Thes...

journal_title：Chest

authors： Chhajed PN,Baty F,Pless M,Somandin S,Tamm M,Brutsche MH

更新日期：2006-12-01 00:00:00

abstract：KEY POINTS:1. Historically, medical ethics focused on the proper conduct of physicians as members of a profession. 2. Bioethics has emerged as a distinct field over the past several decades and has a broader scope than traditional medical ethics. The field of bioethics includes research ethics, public health ethics, or...

journal_title：Chest

authors： Carrese JA,Sugarman J

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:This study reports the effect of thoracentesis on respiratory mechanics and gas exchange in patients receiving mechanical ventilation. STUDY DESIGN:Prospective. SETTING:University hospital. PATIENTS:Eight patient receiving mechanical ventilation with unilateral (n = 7) or bilateral (n = 1) large pleural e...

journal_title：Chest

authors： Doelken P,Abreu R,Sahn SA,Mayo PH

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:FEV1 may remain stable while high-resolution CT (HRCT) appearances deteriorate in children with cystic fibrosis (CF). However, spirometry results commonly decline in older age groups. OBJECTIVES:To compare the rate of decline in HRCT abnormalities and spirometry results over time in an adult cohort with CF....

journal_title：Chest

authors： Judge EP,Dodd JD,Masterson JB,Gallagher CG

更新日期：2006-11-01 00:00:00

abstract：RATIONALE:Pseudomonas aeruginosa lung infection in patients with bronchiectasis, a chronic airway disease that is characterized by episodes of exacerbation, is associated with more severe disease and a higher utilization of health-care resources. Inhaled tobramycin solution reduces the number of acute exacerbations in ...

journal_title：Chest

authors： Bilton D,Henig N,Morrissey B,Gotfried M

更新日期：2006-11-01 00:00:00

abstract：:The American Association of Critical-Care Nurses (AACN) Standards for Establishing and Sustaining Healthy Work Environments and the American College of Chest Physicians (ACCP) Patient-Focused Care Project are complementary initiatives that provide a road map for creating practice environments where interdisciplinary, ...

journal_title：Chest

authors： McCauley K,Irwin RS

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Bronchiectasis and pulmonary infection with nontuberculous mycobacteria (NTM) may be associated with disease-causing mutations in the cystic fibrosis transmembrane regulator (CFTR). METHODS:Fifty adult patients at Stanford University Medical Center with a diagnosis of bronchiectasis and/or pulmonary NTM inf...

journal_title：Chest

authors： Ziedalski TM,Kao PN,Henig NR,Jacobs SS,Ruoss SJ

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to examine the relationship between respiratory symptom intensity and quality and dynamic lung hyperinflation (DH) during induced bronchoconstriction in asthma. PATIENTS AND METHODS:Subjects with asthma (n = 116) underwent baseline spirometry and lung volume measurement follow...

journal_title：Chest

authors： Lougheed MD,Fisher T,O'Donnell DE

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To assess whether the presence and duration of air leaks after lobectomy are associated with an increased incidence of cardiopulmonary complications. METHODS:Propensity score analysis was used on 726 patients undergoing pulmonary lobectomy from 1995 through 2004 to form three well-matched pairs of patients: pa...

journal_title：Chest

authors： Brunelli A,Xiume F,Al Refai M,Salati M,Marasco R,Sabbatini A

更新日期：2006-10-01 00:00:00

abstract：:Individuals continue to smoke despite its numerous proven adverse health effects. Now viewed as a chronic medical condition, health-care professionals are more involved in cessation efforts. Physicians are often the first line of defense, providing intervention through prescription management and counseling. Some insu...

journal_title：Chest

authors： Pohlig C

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The prevalence of COPD is estimated to 4 to 14%. According to the Global Initiative for Chronic Obstructive Lung Disease guidelines, COPD is divided into four stages. Patients with stage IV disease (very severe) have FEV1 < 30% of predicted values and/or respiratory insufficiency. The few studies that exist ...

journal_title：Chest

authors： Stenfors N

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Health-care workers are concerned about the risk of acquiring contagious diseases such as severe acute respiratory syndrome and avian influenza after recent outbreaks. We studied exhaled air and particle dispersion through an oronasal mask attached to a human-patient simulator (HPS) during noninvasive positi...

journal_title：Chest

authors： Hui DS,Hall SD,Chan MT,Chow BK,Tsou JY,Joynt GM,Sullivan CE,Sung JJ

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Average volume-assured pressure support (AVAPS) has been introduced as a new additional mode for a bilevel pressure ventilation (BPV) device (BiPAP; Respironics; Murrysville, PA), but studies on the physiologic and clinical effects have not yet been performed. There is a particular need to better define the ...

journal_title：Chest

authors： Storre JH,Seuthe B,Fiechter R,Milioglou S,Dreher M,Sorichter S,Windisch W

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:Physician productivity, practice expense, resource allocation, facilities, staff, and malpractice are variables in medical practice profitability. The ongoing challenge of collecting reliable and consistent data created an opportunity in 2001 for the American College of Chest Physicians (ACCP) Practice Admin...

journal_title：Chest

authors： Bauer JS,French KD

更新日期：2006-09-01 00:00:00

abstract：CONTEXT:Few studies have examined the effect of nicotine replacement therapy (NRT) in COPD patients. STUDY OBJECTIVE:To evaluate the efficacy of nicotine sublingual tablets and two levels of support for smoking cessation in COPD patients. DESIGN:Double-blind, multicenter, placebo-controlled smoking cessation trial. ...

journal_title：Chest

authors： Tønnesen P,Mikkelsen K,Bremann L

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:To improve communication and decision making related to cardiopulmonary resuscitation (CPR), a greater understanding of the perspectives of hospitalized patients with advanced diseases and their family members are needed. METHODS:In five Canadian hospitals, we administered a face-to-face questionnaire to ol...

journal_title：Chest

authors： Heyland DK,Frank C,Groll D,Pichora D,Dodek P,Rocker G,Gafni A

更新日期：2006-08-01 00:00:00

abstract：STUDY OBJECTIVE:Spirometry is performed to monitor lung health, but variability between tests can hinder recognition of excessive FEV(1) declines. We sought to describe the relationship between FEV(1) changes over 1 to 5 years and FEV(1) declines over longer terms, using 21,821 test results from 1,884 workers who parti...

journal_title：Chest

authors： Wang ML,Avashia BH,Petsonk EL

更新日期：2006-08-01 00:00:00

abstract：:Proteomics is the study of the entire protein complement of the genome (the proteome) in a biological system. Proteomic studies require a multidisciplinary approach and have only been practical with the convergence of technical and methodologic improvements including the following: advances in mass spectrometry and ge...

journal_title：Chest

authors： Bowler RP,Ellison MC,Reisdorph N

更新日期：2006-08-01 00:00:00

abstract：:Two rules of good graphs are presented and explicated. ...

journal_title：Chest

authors： Green J

更新日期：2006-08-01 00:00:00

abstract：:Patient-focused or patient-centered care is not a new concept, but its value has been overlooked in preference to the technology-based, disease-centered model that has prevailed in medicine for the last 50 years. Patient-focused care includes four broad areas of intervention: communication with patients, partnerships,...

journal_title：Chest

authors： Irwin RS,Richardson ND

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Nerve growth factor (NGF) is a neurotrophic cytokine with immunomodulatory activity. NGF contributes to neurogenic inflammation and has been described in asthma and idiopathic pulmonary fibrosis. OBJECTIVES:To identify and quantify NGF in serum and peripheral blood lymphocyte cultures from pigeon fanciers, ...

journal_title：Chest

authors： McSharry CP,Fraser I,Chaudhuri R,Anderson K,Bourke SJ,Thomson NC,Boyd G

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Emphysema is the only smoking-related disease in which white patients have higher prevalence and higher attributable mortality rates than African-American patients. Epidemiologic studies have not addressed, nor explained, the observed racial differences in emphysema. STUDY OBJECTIVES:To determine whether wh...

journal_title：Chest

authors： Chatila WM,Hoffman EA,Gaughan J,Robinswood GB,Criner GJ,National Emphysema Treatment Trial Research Group.

更新日期：2006-07-01 00:00:00

abstract：STUDY OBJECTIVE:Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. Immunosuppressive therapy should be better evaluated in this setting. STUDY DESIGN:Monocentric retrospective study. ...

journal_title：Chest

authors： Sanchez O,Sitbon O,Jaïs X,Simonneau G,Humbert M

更新日期：2006-07-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP), a major cause of ICU infection, results in high morbidity, mortality, and health-care costs. Multiple risk factors for VAP involve complex host factors and ubiquitous pathogens that require several different types of prevention strategies. Prevention efforts should focus on reduc...

journal_title：Chest

authors： Craven DE

更新日期：2006-07-01 00:00:00

abstract：STUDY OBJECTIVE:To investigate the efficacy and safety profiles of corticosteroid therapy in severe acute respiratory syndrome (SARS) patients. DESIGN:Four hundred one of 1,278 SARS cases treated in Guangzhou China between December 2002 and June 2003 fulfilled the diagnostic criteria issued by the World Health Organiz...

journal_title：Chest

authors： Chen RC,Tang XP,Tan SY,Liang BL,Wan ZY,Fang JQ,Zhong N

更新日期：2006-06-01 00:00:00